Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389037 | 1.00 | TSHR (0.75) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL8845137 | 1.00 | TSHR (0.75) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL1512983 | 1.00 | TSHR (0.75) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL8844654 | 1.00 | TSHR (0.75) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL664291 | 0.95 | TSHR (0.67) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL8846029 | 0.92 | TSHR (0.59) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL9420975 | 0.90 | TSHR (0.64) | TSHRTDP1POLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL15284903 | 0.89 | TSHR (0.67) | TSHRTDP1POLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL11249801 | 0.89 | TSHR (0.67) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL1109940 | 0.89 | TSHR (0.57) | TSHRTDP1THRBFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110211-B2 | Medicated coatings for implantable medical devices including polyacrylates | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| US-8058341-B2 | Improved adhesion under wet or low-temperature conditions using a blend of acrylic or rubber base and a hydrophilic polymer selected from polyalkylene glycols, -vinylpyrrolidone, -vinyl alcohols and -(meth)acrylic acid | NITTO DENKO CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-8039103-B2 | Adhesion against the dewing surface or wetting surface and having good peeling-preventing properties under constant load | NITTO DENKO CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20110045444-A1 | DENTAL FILLING COMPOSITION COMPRISING HYPERBRANCHED COMPOUND | 3M INNOVATIVE PROPERTIES COMPANY | 2011-02-24 | — | — | US | disclosed |
| US-20110034994-A1 | STENTS WITH DRUG-CONTAINING AMPHIPHILIC POLYMER COATING | LEWIS ANDREW L | 2011-02-10 | — | — | US | disclosed |
| US-20110034995-A1 | STENTS WITH DRUG-CONTAINING AMPHIPHILIC POLYMER COATING | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2011-02-10 | — | — | US | disclosed |
| US-7396868-B2 | Moist surface adhesion; constant load peeling; workability; combination of high molecular weight polyalkylene glycol with polyvinylpyrrolidone, polyvinyl alcohol or acrylic ester copolymer; solvent free | NITTO DENKO CORPORATION (JP) | 2008-07-08 | — | — | US | disclosed |
| US-20050075444-A1 | Aqueous dispersion type pressure-sensitive adhesive composition and pressure-sensitive adhesive product | NITTO DENKO CORPORATION | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045444-A1 | DENTAL FILLING COMPOSITION COMPRISING HYPERBRANCHED COMPOUND | MMAB, CAD, MTHFD2 | TSHR 4046/4885TDP1 570/4885POLB 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.