Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.77 |
| ▸ | CTSL | P07711 | 17/20 | 0.77 |
| ▸ | CTSS | P25774 | 13/20 | 0.77 |
| ▸ | CTSB | P07858 | 5/20 | 0.77 |
| ▸ | CTSV | O60911 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643547 | 1.00 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6643546 | 1.00 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105285 | 0.94 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099237 | 0.94 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4768473 | 0.94 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105280 | 0.94 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4792549 | 0.92 | CTSK (0.80) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6405567 | 0.92 | CTSK (0.80) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5093147 | 0.89 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5093145 | 0.89 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | claimed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | claimed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | claimed |