Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | HRH2 | P25021 | 8/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6649932 | 0.90 | HTR6 (0.54) | HTR6HRH2RORCHTR2AHTR2C | |
| SCHEMBL5770874 | 0.90 | HTR6 (0.70) | HTR6HRH2DRD2SLC6A4HTR2A | |
| Oxalic Acid SCHEMBL6646744 | 0.87 | HTR6 (0.51) | HTR6HRH2RORCDRD2HTR2A | |
| Oxalic Acid SCHEMBL5372086 | 0.86 | HTR6 (0.65) | HTR6HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6646628 | 0.86 | HTR6 (0.49) | HTR6HRH2RORCDRD2SLC6A4 | |
| Oxalic Acid SCHEMBL6649675 | 0.85 | HTR6 (0.63) | HTR6RORCDRD2SLC6A4 | |
| SCHEMBL5767852 | 0.84 | HTR6 (0.72) | HTR6HRH2DRD2SLC6A4HTR2A | |
| SCHEMBL5769224 | 0.83 | HTR6 (0.50) | HTR6HRH2HTR2AHTR2CHTR2B | |
| Oxalic Acid SCHEMBL6648319 | 0.82 | HTR6 (0.53) | HTR6HRH2RORC | |
| Oxalic Acid SCHEMBL5375349 | 0.80 | HTR6 (0.66) | HTR6HRH2DRD2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377580-A2 | BENZENESULFONIC ACID INDOL-5-YL ESTERS AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2004-01-07 | — | — | EP | claimed |
| WO-2002060871-A2 | BENZENESULFONIC ACID INDOL-5-YL ESTERS AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2002-08-08 | — | — | WO | claimed |