Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 19/20 | 0.79 |
| ▸ | NOS3 | P29474 | 17/20 | 0.79 |
| ▸ | NOS2 | P35228 | 17/20 | 0.79 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646596 | 0.88 | NOS1 (1.00) | NOS1NOS3NOS2PNMT | |
| SCHEMBL6643807 | 0.80 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6645947 | 0.77 | NOS1 (0.68) | NOS1NOS3NOS2 | |
| SCHEMBL6645211 | 0.77 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6646529 | 0.73 | NOS1 (0.67) | NOS1NOS3NOS2 | |
| SCHEMBL6643460 | 0.73 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6646269 | 0.73 | NOS1 (0.79) | NOS1NOS3NOS2 | |
| SCHEMBL6644831 | 0.73 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6642652 | 0.71 | NOS1 (0.63) | NOS1NOS3NOS2 | |
| SCHEMBL6642217 | 0.71 | NOS1 (1.00) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391887-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; CARDIOVASCULAR DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | claimed |
| EP-1054869-B1 | 3,4-DIHYDROQUINOLINE DERIVATIVES AS NITROGEN MONOXIDE SYNTHASE (NOS) INHIBITORS | SCHERING AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6391887-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; CARDIOVASCULAR DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | disclosed |