Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379965 | 0.96 | KMT2A (0.76) | MEN1KMT2APOLBLMNAAKR1C3 | |
| SCHEMBL29941108 | 0.86 | KMT2A (0.82) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 | |
| SCHEMBL21067983 | 0.86 | KMT2A (0.82) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 | |
| SCHEMBL6650042 | 0.82 | KMT2A (0.70) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 | |
| SCHEMBL693455 | 0.80 | KMT2A (1.00) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 | |
| SCHEMBL7647926 | 0.79 | KMT2A (0.55) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL20389408 | 0.77 | KMT2A (0.77) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 | |
| SCHEMBL12793350 | 0.77 | KMT2A (0.77) | MEN1KMT2APOLBLMNAAKR1C3 | |
| SCHEMBL13302259 | 0.77 | KMT2A (0.77) | MEN1KMT2APOLBLMNAAKR1C3 | |
| SCHEMBL5915341 | 0.77 | KMT2A (0.77) | MEN1KMT2APOLBAKR1C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483244-A1 | CYCLIC N-SUBSTITUTED ALPHA IMINOCARBOXYLIC ACIDS FOR SELECTIVELY INHIBITING COLLAGENASE | Aventis Pharma Deutschland GmbH (DE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074489-A1 | CYCLIC N-SUBSTITUTED ALPHA IMINOCARBOXYLIC ACIDS FOR SELECTIVELY INHIBITING COLLAGENASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-12 | — | — | WO | disclosed |