Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.74 |
| ▸ | CDC25B | P30305 | 1/20 | 0.74 |
| ▸ | CASP3 | P42574 | 1/20 | 0.74 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.74 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.74 |
| ▸ | PARP1 | P09874 | 9/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646122 | 0.88 | APAF1 (0.59) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6644982 | 0.88 | APAF1 (0.59) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6644935 | 0.87 | APAF1 (0.57) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL19051444 | 0.86 | APAF1 (1.00) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6646477 | 0.85 | APAF1 (0.59) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6649052 | 0.85 | APAF1 (0.65) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6647858 | 0.83 | TNKS (0.55) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6648354 | 0.83 | APAF1 (0.50) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6646110 | 0.83 | APAF1 (0.61) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL6647353 | 0.77 | APAF1 (0.76) | APAF1CDC25BCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | claimed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | claimed |
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | PARP11, PARP1, CD38 | APAF1 318/4885CDC25B 3854/4885CASP3 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.