SCHEMBL6645772

SCHEMBL6645772

CCCCC(=O)NC1CCC(C(C)(C)C)CC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
KMT2A Q03164 1/20 0.54
GNAI3 P08754 1/20 0.53
GNAO1 P09471 1/20 0.53
GNAI1 P63096 1/20 0.53
EPHX1 P07099 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
CNR2 P34972 8/20 0.49
CNR1 P21554 7/20 0.49
SMYD3 Q9H7B4 1/20 0.46
EPHX2 P34913 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28340112 0.94 GNAI3 (0.61) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL4078312 0.91 EPHX1 (0.56) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL3309908 0.88 MEN1 (0.65) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL4078313 0.87 EPHX1 (0.51) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL14242712 0.82 EPHX1 (0.58) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL3551415 0.82 GNAI3 (0.72) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL7753207 0.81 EPHX1 (0.53) EPHX1SMYD3EPHX2
SCHEMBL11571826 0.80 GNAI3 (0.75) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL1457137 0.80 GNAI3 (0.75) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL8361102 0.80 GNAI3 (0.75) MEN1ALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389460-A1 CXCR4-ANTAGONISTIC DRUGS COMPRISING NITROGEN-CONTAINING COMPOUND Kureha Chemical Industry Co., Ltd. (JP) 2004-02-18 EP disclosed