Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642885 | 0.94 | KMT2A (0.59) | PDE5AKMT2AKDM4E | |
| SCHEMBL6646508 | 0.93 | PDE5A (0.54) | PDE5AKMT2AKDM4E | |
| SCHEMBL6641389 | 0.90 | PDE5A (0.55) | PDE5AKMT2AKDM4E | |
| SCHEMBL6646921 | 0.90 | PDE5A (0.53) | PDE5AKMT2AKDM4E | |
| SCHEMBL24307141 | 0.89 | PDE5A (0.62) | PDE5AKMT2AKDM4E | |
| SCHEMBL6640382 | 0.88 | PDE5A (0.73) | PDE5A | |
| SCHEMBL6644911 | 0.86 | KMT2A (0.59) | PDE5AKMT2AKDM4E | |
| SCHEMBL6642909 | 0.85 | PDE5A (0.56) | PDE5AKMT2AKDM4E | |
| SCHEMBL6646009 | 0.84 | PDE5A (0.65) | PDE5A | |
| SCHEMBL6647593 | 0.84 | PDE5A (0.74) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257553-B1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |