Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 11/20 | 0.67 |
| ▸ | SRC | P12931 | 6/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261283 | 0.89 | RIPK2 (0.70) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL5618684 | 0.87 | RIPK2 (0.68) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL8357880 | 0.87 | RIPK2 (0.72) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL8356091 | 0.86 | RIPK2 (0.74) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL8308306 | 0.86 | RIPK2 (0.74) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL8362338 | 0.84 | RIPK2 (0.64) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL24410875 | 0.82 | RIPK2 (0.61) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL4257226 | 0.82 | RIPK2 (0.61) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL8361716 | 0.82 | SRC (0.63) | RIPK2SRCLCKKDRTGFBR1 | |
| SCHEMBL16247045 | 0.79 | RIPK2 (1.00) | RIPK2SRCLCKKDRTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436265-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1436265-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003072541-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-04 | — | — | WO | disclosed |