SCHEMBL6646362

SCHEMBL6646362

[O]COc1ccccc1-c1[c]cccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
DRD1 P21728 4/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD5 P21918 1/20 0.32
DRD3 P35462 1/20 0.32
RAB9A P51151 2/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.31
TSHR P16473 1/20 0.31
PTPRC P08575 1/20 0.30
CTSL P07711 1/20 0.30
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30
RXRA P19793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10500436 0.84 TP53 (0.33) TDP1L3MBTL1RAB9ATP53MAPK1
SCHEMBL7673600 0.82 TDP1 (0.36) TDP1L3MBTL1HPGDALDH1A1MAPT
SCHEMBL447310 0.82 ALDH1A1 (0.44) TDP1L3MBTL1HPGDALDH1A1MAPT
SCHEMBL6536573 0.82 DRD1 (0.45) DRD1DRD2DRD4DRD5DRD3
SCHEMBL3141587 0.79
SCHEMBL9703336 0.79 TP53 (0.44) ALDH1A1RAB9ATP53MAPK1HTR7
SCHEMBL3731514 0.79 BRD4 (0.48) TDP1L3MBTL1MAPTDRD2MAPK1
SCHEMBL3867574 0.76 CYP1A2 (0.47) MAPT
SCHEMBL336434 0.76 APP (0.47) TDP1HPGDALDH1A1MAPTRAB9A
SCHEMBL8168509 0.73 PDE5A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1386901-B1 Method for producing an optically active beta-amino acid TAKASAGO PERFUMERY CO LTD (JP) 2015-07-01 EP disclosed
EP-1386901-A1 Method for producing an optically active beta-amino acid Takasago International Corporation (JP) 2004-02-04 EP disclosed