SCHEMBL6646409

SCHEMBL6646409

CC(C)C(Cl)c1cncnc1C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10073280 0.83 ALDH1A1 (0.32)
SCHEMBL26273251 0.82
SCHEMBL6644895 0.81
SCHEMBL6643185 0.81 PDE2A (0.40)
SCHEMBL8576655 0.80 PDE2A (0.35)
SCHEMBL6641950 0.78 ALDH1A1 (0.33)
SCHEMBL8580032 0.76 CYP11B1 (0.34)
SCHEMBL6646004 0.74 ATF1 (0.31)
SCHEMBL8581484 0.71 ALDH1A1 (0.31)
SCHEMBL8566396 0.70 PDE2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238343-C Pyrimidine derivatives and herbicides containing the same KUMIAL CHEMICAL INDUSTRY CO LT (JP) 2006-01-25 CN disclosed
US-6806230-B1 NITROGEN COMPOUNDS SUCH AS N-METHYL-N-(2-METHYL-1-(4-TRIFLUORO METHYLPYRIMIDIN-5-YL)PROPYL)PHENYLACETAMIDE, USED FOR PREFERENTIAL CONTROL OF WEEDS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-10-19 US disclosed
EP-1211246-B1 PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME KUMIAI CHEMICAL INDUSTRY CO (JP) 2004-02-25 EP disclosed
CN-1372552-A Pyrimidine derivatives and herbicides containing the same KUMIAL CHEMICAL INDUSTRY CO LT (JP) 2002-10-02 CN disclosed
EP-1211246-A1 PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2002-06-05 EP disclosed