Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648890 | 0.98 | PARP1 (0.56) | PARP1HTR1AHTR3APKML3MBTL1 | |
| SCHEMBL6651055 | 0.87 | PARP1 (0.45) | PARP1HTR1AHTR3AHTR2CTNKS | |
| SCHEMBL6649328 | 0.86 | PARP1 (0.44) | PARP1HTR1AHTR3AHTR2CTNKS | |
| SCHEMBL6418477 | 0.85 | PARP1 (0.43) | PARP1HTR2CTNKSTNKS2 | |
| SCHEMBL6650044 | 0.85 | PARP1 (0.51) | PARP1HTR1AHTR3A | |
| Hydrochloric Acid SCHEMBL7018458 | 0.81 | PARP1 (0.55) | PARP1 | |
| SCHEMBL7023192 | 0.78 | PARP1 (0.49) | PARP1 | |
| SCHEMBL467535 | 0.77 | PARP1 (0.60) | PARP1 | |
| SCHEMBL7017894 | 0.77 | PARP1 (0.48) | PARP1 | |
| SCHEMBL7017660 | 0.77 | PARP1 (0.60) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469854-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063874-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |