Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059298 | 0.79 | GSK3B (0.49) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL1059295 | 0.79 | GSK3B (0.49) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL20413674 | 0.79 | KDM4E (0.56) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL20413680 | 0.75 | CYP1A2 (0.64) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL1055994 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL1058015 | 0.75 | KDM4E (0.49) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL1055993 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL1058014 | 0.75 | KDM4E (0.49) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL1058558 | 0.73 | GSK3B (0.55) | KDM4EHPGDALDH1A1CCNA2CDK2 | |
| SCHEMBL1058560 | 0.73 | GSK3B (0.55) | KDM4EHPGDALDH1A1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417349-A2 | NOVEL MOLECULAR TARGET FOR NEUROTOXICITY | Exonhit Therapeutics S.A. (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016563-A2 | NOVEL MOLECULAR TARGET FOR NEUROTOXICITY | EXONHIT THERAPEUTICS SA (FR) | 2003-02-27 | — | — | WO | disclosed |