SCHEMBL664823

SCHEMBL664823

CCCC=C1C=C(C)OC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
POLB P06746 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TRPA1 O75762 2/20 0.43
KDM4E B2RXH2 2/20 0.42
NSD2 O96028 1/20 0.42
DNMT1 P26358 1/20 0.42
APEX1 P27695 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PPARG P37231 2/20 0.35
ALDH1A1 P00352 3/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.35
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL663297 0.89 L3MBTL1 (0.49) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL664888 0.87 POLB (0.47) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL664842 0.86 POLB (0.46) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL665965 0.86 POLB (0.46) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL663161 0.86 POLB (0.46) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL666235 0.86 POLB (0.46) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL662264 0.84 MAPT (0.55) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL16080097 0.73
SCHEMBL663388 0.73
SCHEMBL19522688 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389298-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
EP-1985680-B2 Composition comprising a HFC-1234ze isomer CHEMOURS CO FC LLC (US) 2022-06-29 EP disclosed
US-20050156139-A1 1-Ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US disclosed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US disclosed
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed
US-20050109978-A1 Refrigerant compositions comprising performance enhancing additives LECK THOMAS J (US) 2005-05-26 US disclosed
WO-2005014565-A2 CIS-3,5-DISUBSTITUTED-DIHYDRO-FURAN-2-ONES AND THE PREPARATION AND USE THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-02-17 WO disclosed
US-6841088-B2 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-01-11 US disclosed