Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.66 |
| ▸ | CTSL | P07711 | 18/20 | 0.66 |
| ▸ | CTSS | P25774 | 14/20 | 0.66 |
| ▸ | CTSB | P07858 | 6/20 | 0.66 |
| ▸ | CTSV | O60911 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842089 | 0.87 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7485959 | 0.83 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5093126 | 0.81 | CTSK (0.86) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14040700 | 0.80 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131372 | 0.80 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6835492 | 0.80 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6836234 | 0.80 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6838160 | 0.80 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL12270440 | 0.79 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131370 | 0.79 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392657-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1392657-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003053331-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |