Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 9/20 | 0.69 |
| ▸ | APAF1 | O14727 | 5/20 | 0.69 |
| ▸ | CASP3 | P42574 | 5/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.69 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | UBE2I | P63279 | 2/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051444 | 0.82 | APAF1 (1.00) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6648831 | 0.81 | CDC25B (0.64) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6648820 | 0.80 | APAF1 (0.63) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6647610 | 0.80 | CDC25B (0.63) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6649052 | 0.79 | APAF1 (0.65) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6646110 | 0.79 | APAF1 (0.61) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6644553 | 0.78 | TNKS (0.48) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL31378554 | 0.78 | APAF1 (0.60) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL15332563 | 0.77 | CDC25B (0.63) | CDC25BAPAF1CASP3SENP8SENP7 | |
| SCHEMBL6644982 | 0.77 | APAF1 (0.59) | CDC25BAPAF1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | claimed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | claimed |
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | PARP11, PARP1, CD38 | CDC25B 3854/4885APAF1 318/4885CASP3 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.