Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | RPS27 | P42677 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254988 | 0.91 | ADORA3 (0.53) | CTNNB1TCF7L2KMT2AMEN1AURKA | |
| SCHEMBL29371671 | 0.91 | ADORA3 (0.53) | CTNNB1TCF7L2KMT2AMEN1AURKA | |
| SCHEMBL6613383 | 0.84 | CTNNB1 (0.47) | CTNNB1TCF7L2KMT2AMEN1LMNA | |
| SCHEMBL6479650 | 0.83 | MEN1 (0.54) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL6489855 | 0.81 | ADORA3 (0.49) | CTNNB1TCF7L2KMT2AMEN1AURKA | |
| SCHEMBL2012739 | 0.80 | ADORA2A (0.47) | CTNNB1TCF7L2AURKAAURKBLMNA | |
| SCHEMBL939862 | 0.80 | ADORA2A (0.47) | CTNNB1TCF7L2AURKAAURKBLMNA | |
| SCHEMBL6480019 | 0.80 | ADORA3 (0.48) | CTNNB1TCF7L2KMT2AMEN1MAPK8 | |
| SCHEMBL939909 | 0.80 | CTNNB1 (0.49) | CTNNB1TCF7L2AURKAAURKBLMNA | |
| SCHEMBL940842 | 0.79 | FLT3 (0.47) | CTNNB1TCF7L2AURKAAURKBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390349-A1 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | Sanofi-Aventis (FR) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096879-A1 | AMINOQUINOLINE AND AMINOPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI-SYNTHELABO (FR) | 2002-12-05 | — | — | WO | disclosed |