Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351517 | 0.89 | BACE1 (0.69) | BACE1BACE2 | |
| SCHEMBL3351524 | 0.89 | BACE1 (0.69) | BACE1BACE2 | |
| SCHEMBL6893064 | 0.81 | BACE1 (0.54) | BACE1BACE2 | |
| SCHEMBL3346953 | 0.75 | BACE1 (0.72) | BACE1BACE2 | |
| SCHEMBL3346959 | 0.75 | BACE1 (0.72) | BACE1BACE2 | |
| SCHEMBL3355738 | 0.75 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL3355743 | 0.75 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL5121674 | 0.75 | BACE1 (0.47) | BACE1BACE2 | |
| SCHEMBL5350790 | 0.74 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL16578190 | 0.74 | BACE1 (0.91) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |