Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357959 | 0.89 | BACE1 (0.68) | BACE1BACE2CTSD | |
| SCHEMBL3357965 | 0.89 | BACE1 (0.68) | BACE1BACE2CTSD | |
| SCHEMBL3353181 | 0.81 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL3353178 | 0.81 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL6648928 | 0.81 | BACE1 (0.54) | BACE1BACE2 | |
| SCHEMBL3354246 | 0.78 | BACE1 (0.72) | BACE1BACE2CTSD | |
| SCHEMBL3354242 | 0.78 | BACE1 (0.72) | BACE1BACE2CTSD | |
| SCHEMBL3355738 | 0.75 | BACE1 (0.77) | BACE1BACE2CTSD | |
| SCHEMBL3355743 | 0.75 | BACE1 (0.77) | BACE1BACE2CTSD | |
| SCHEMBL5350790 | 0.74 | BACE1 (0.79) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |