Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275907 | 0.80 | DAO (0.51) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL7584888 | 0.79 | MEN1 (0.47) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL5265643 | 0.78 | DAO (0.50) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL5265071 | 0.78 | MEN1 (0.46) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL14701887 | 0.77 | DAO (0.56) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL11431122 | 0.77 | DAO (0.60) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL10296643 | 0.76 | DAO (0.51) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL444120 | 0.75 | DAO (0.58) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL6219061 | 0.74 | CHRM2 (0.53) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL792991 | 0.74 | DAO (0.56) | MEN1CYP1A2KMT2ADAOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |