Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651211 | 0.98 | PAOX (0.43) | PAOXALDH1A1ACHECES2DGKA | |
| SCHEMBL6648343 | 0.91 | ALDH1A1 (0.41) | PAOXALDH1A1ACHECES2LMNA | |
| SCHEMBL8818734 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNATSHR | |
| SCHEMBL21551929 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNATSHR | |
| SCHEMBL8432837 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNATSHR | |
| SCHEMBL10018323 | 0.80 | PAOX (0.41) | PAOXALDH1A1ACHECES2TSHR | |
| SCHEMBL9955793 | 0.80 | SOAT1 (0.36) | ALDH1A1DGKATSHRCYP3A4 | |
| SCHEMBL16294270 | 0.79 | TSHR (0.54) | ALDH1A1DGKALMNATSHR | |
| SCHEMBL18038087 | 0.79 | TSHR (0.54) | ALDH1A1DGKALMNATSHR | |
| SCHEMBL16294179 | 0.79 | TSHR (0.54) | ALDH1A1DGKALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | claimed |
| EP-1095944-B1 | Single-carbon bridged bis cyclopentadienyl compounds and metallocene complexes thereof | REPSOL QUIMICA SA (ES) | 2004-03-17 | — | — | EP | disclosed |
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | disclosed |
| EP-1095944-A1 | Single-carbon bridged bis cyclopentadienyl compounds and metallocene complexes thereof | REPSOL QUIMICA S.A. (ES) | 2001-05-02 | — | — | EP | disclosed |