Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.51 |
| ▸ | NOS3 | P29474 | 6/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630681 | 0.85 | NOS1 (0.52) | NOS1NOS3CHRM2CHRM4DRD2 | |
| SCHEMBL6630596 | 0.84 | NOS1 (0.43) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6630688 | 0.83 | NOS1 (0.43) | NOS1NOS3 | |
| SCHEMBL6630895 | 0.82 | NOS1 (0.46) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6618963 | 0.80 | NOS1 (0.41) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6631029 | 0.80 | NOS1 (0.47) | NOS1NOS3CHRM2CHRM4 | |
| SCHEMBL6630085 | 0.79 | NOS1 (0.50) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6632677 | 0.79 | NOS1 (0.48) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6621811 | 0.79 | NOS1 (0.44) | NOS1NOS3CHRM2CHRM4HTR1A | |
| SCHEMBL6622190 | 0.79 | NOS1 (0.42) | NOS1NOS3CHRM2CHRM4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471055-A1 | 6-phenylpyridyl-2-amine derivatives | PFIZER INC. (US) | 2004-10-27 | — | — | EP | claimed |
| US-6235747-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC. | 2001-05-22 | — | — | US | claimed |
| US-6235747-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC. | 2001-05-22 | — | — | US | disclosed |