⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143563 | 0.75 | — | — | |
| SCHEMBL27351274 | 0.74 | — | — | |
| SCHEMBL19055557 | 0.64 | — | — | |
| SCHEMBL4743726 | 0.63 | — | — | |
| SCHEMBL17851152 | 0.63 | — | — | |
| SCHEMBL14678811 | 0.61 | — | — | |
| SCHEMBL28164240 | 0.60 | — | — | |
| SCHEMBL2704951 | 0.60 | — | — | |
| SCHEMBL19036577 | 0.60 | — | — | |
| SCHEMBL18567263 | 0.60 | ADH1B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-B | Benzo piperazine composition as BET bromine domain inhibitor | 福马疗法公司 | 2019-06-07 | — | — | CN | claimed |
| CN-104870440-B | Bicyclic heterocycles and its therapeutical uses | 阿斯特克斯治疗有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-105143207-B | Substituted pyridine and substituted pyrazine compounds as PDE4 inhibitors | 达特神经科学(开曼)有限公司 | 2018-04-24 | — | — | CN | claimed |
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | claimed |
| CN-107216351-A | Chlopyrifos and preparation method thereof | 重庆华歌生物化学有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-107108534-A | Probes for Imaging Huntingtin | CHDI基金会股份有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107108597-A | Dopamine D3 receptor antagonist compounds | 英立维尔英国有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107105655-A | Probe for being imaged Huntington protein | CHDI基金会股份有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107074817-A | Probes for Imaging Huntingtin | CHDI基金会股份有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-103038233-B | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2017-06-20 | — | — | CN | claimed |
| CN-101511186-A | Dihydropyridine compounds and compositions for headache | EISAI CO LTD (JP) | 2009-08-19 | — | — | CN | claimed |
| CN-101304970-A | Amorphous form of 1, 2-dihydropyridine compound | EISAI R&D MAN CO LTD (JP) | 2008-11-12 | — | — | CN | claimed |
| CN-101258131-A | As 5-HT2c6-aralkylamino-2, 3,4, 5-tetrahydro-1H-benzo [ d ] receptors as agonists]Aza * | LILLY CO ELI (US) | 2008-09-03 | — | — | CN | claimed |
| CN-1942443-A | 1, 2-dihydropyridine compound crystal and preparation method thereof | EISAI R&D MAN CO LTD (JP) | 2007-04-04 | — | — | CN | claimed |
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |
| CN-1083835-C | Preparation method of 3,3, 5-trichloroglutarimide | DOW AGROSCIENCES CORP (US) | 2002-05-01 | — | — | CN | claimed |
| CN-1163611-A | Preparation method of 3, 3, 5-trichloroglutarimide | DOWELANCO CO (US) | 1997-10-29 | — | — | CN | claimed |
| CN-1027259-C | Improved process for preparation of 3,5,6-trichloropyridin-2-01 | DOW CHEMICAL CO (US) | 1995-01-04 | — | — | CN | claimed |
| CN-1047281-A | Preparation 3,5, the improving one's methods of 6-trichloropyridine-2-alcohol | DOW CHEMICAL CO (US) | 1990-11-28 | — | — | CN | claimed |