Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | GALR3 | O60755 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650777 | 0.90 | PDE3B (0.59) | PDE3BPDE3AABCB11MAOAADORA2A | |
| SCHEMBL10353457 | 0.79 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL16157203 | 0.79 | PDE3B (0.67) | PDE3BPDE3AABCB11MAOAADORA2A | |
| SCHEMBL9516148 | 0.79 | PDE3B (0.67) | PDE3BPDE3AABCB11MAOAADORA2A | |
| SCHEMBL9182320 | 0.76 | PDE3B (0.64) | PDE3BPDE3AABCB11MAOAADORA2A | |
| SCHEMBL992766 | 0.75 | GALR3 (0.72) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL16157195 | 0.75 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10619956 | 0.75 | PDE3B (0.56) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7304897 | 0.74 | PDE3B (0.59) | PDE3BPDE3AABCB11MAOAADORA2A | |
| SCHEMBL16156959 | 0.74 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2282328-A | — | — | None | — | — | JP | disclosed |
| CN-1148190-C | Immunodulatory drug composition | ������������ʽ���� | 2004-05-05 | — | — | CN | disclosed |
| EP-1123703-B1 | IMMUNOMODULATORY DRUG COMPOSITION | TORAY INDUSTRIES (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6710046-B1 | A METHOD OF TREATMENT OF RHEUMATISM, HEPATITIS OR PANCREATITIS COMPRISING THE STEP OF ADMINISTERING, TO A PATIENT, A BENZIMIDAZOLE | TORAY INDUSTRIES, INC. (JP) | 2004-03-23 | — | — | US | disclosed |
| CN-1314815-A | Immunodulatory drug composition | MATSUMORI AKIRA (JP) | 2001-09-26 | — | — | CN | disclosed |
| EP-1123703-A1 | IMMUNOMODULATORY DRUG COMPOSITION | Matsumori, Akira (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-0330052-B1 | Use of benzimidazoles for preparing a medicine with an anti-ischemial activity on the heart, and combinations with betablockers or bradycardics | THOMAE GMBH DR K (DE) | 1993-12-15 | — | — | EP | disclosed |
| JP-H02282328-A | POSITIVELY INOTROPIC MEDICINAL COMPOSITION AND ITS PRODUCTION | DR KARL THOMAE GMBH | 1990-11-19 | — | — | JP | disclosed |
| EP-0330052-A2 | Use of benzimidazoles for preparing a medicine with an anti-ischemial activity on the heart, and combinations with betablockers or bradycardics | Dr. Karl Thomae GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |