Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31671081 | 0.83 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL15058849 | 0.82 | KMT2A (0.55) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL8612414 | 0.80 | KMT2A (0.54) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL44676 | 0.79 | KMT2A (0.58) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL29598813 | 0.78 | FABP5 (0.54) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL7767154 | 0.78 | FABP5 (0.54) | KMT2AEPHX2FABP5FABP7CA1 | |
| Formic Acid SCHEMBL27520493 | 0.78 | KMT2A (0.44) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL14944678 | 0.78 | KMT2A (0.49) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL18154892 | 0.78 | KMT2A (0.39) | KMT2AEPHX2FABP5FABP7CA1 | |
| SCHEMBL7720044 | 0.77 | KMT2A (0.58) | KMT2AEPHX2FABP5FABP7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421107-A1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | Abbott Laboratories (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030050246-A1 | Peptides having antiangiogenic activity | ABBOTT LABORATORIES | 2003-03-13 | — | — | US | disclosed |
| US-20030045477-A1 | Peptides having antiangiogenic activity | ABBOTT LABORATORIES | 2003-03-06 | — | — | US | disclosed |
| WO-2003011896-A1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LABORATORIES (US) | 2003-02-13 | — | — | WO | disclosed |