SCHEMBL8612414

SCHEMBL8612414

NC(=O)OC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
FABP5 Q01469 3/20 0.49
FABP7 O15540 2/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
EPHX2 P34913 1/20 0.47
HTR2A P28223 1/20 0.43
CASP3 P42574 2/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15058849 0.90 KMT2A (0.55) KMT2AFABP5FABP7CA1CA2
SCHEMBL30042128 0.86 KMT2A (0.59) KMT2AFABP5FABP7CA1CA2
SCHEMBL113270 0.86 KMT2A (0.59) KMT2AFABP5FABP7CA1CA2
SCHEMBL29362617 0.86 KMT2A (0.59) KMT2AFABP5FABP7CA1CA2
SCHEMBL44676 0.86 KMT2A (0.58) KMT2AFABP5FABP7CA1CA2
SCHEMBL7767154 0.85 FABP5 (0.54) KMT2AFABP5FABP7CA1CA2
SCHEMBL29598813 0.85 FABP5 (0.54) KMT2AFABP5FABP7CA1CA2
Hydrochloric Acid SCHEMBL1234617 0.85 KMT2A (0.57) KMT2AFABP5FABP7CA1CA2
Ammonia Solution, Strong SCHEMBL16430851 0.85 KMT2A (0.57) KMT2AFABP5FABP7CA1CA2
SCHEMBL7720044 0.84 KMT2A (0.58) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
US-12415171-B2 Regulation of DNA synthesis by nucleotides linked to protecting groups MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-09-16 US disclosed
EP-4313156-B1 DISULFIDE-BASED PRODRUG COMPOUNDS UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2025-08-06 EP disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-12252739-B2 Selectively controllable cleavable linkers MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-03-18 US disclosed
US-20250075259-A1 SELECTIVELY CONTROLLABLE CLEAVABLE LINKERS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-03-06 US disclosed
WO-2025024822-A2 PROCESSES FOR MAKING ARYL COMPOUNDS THAT MODULATE IKZF2 Plexium, Inc. (US) 2025-01-30 WO disclosed
CN-119255997-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2025-01-03 CN disclosed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US disclosed
EP-4413149-A1 REGULATION OF DNA SYNTHESIS BY NUCLEOTIDES LINKED TO PROTECTING GROUPS Microsoft Technology Licensing, LLC (US) 2024-08-14 EP disclosed
US-10131658-B2 Anti-alphavbeta1 integrin compounds and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-11-20 US disclosed
US-20180312500-A9 ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-11-01 US disclosed
US-20160376266-A1 ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS UNIV CALIFORNIA (US) 2016-12-29 US disclosed
CN-105154498-A Semi-recombinant preparation of GLP-1 analogues NOVO NORDISK AS 2015-12-16 CN disclosed
CN-101910193-A Semi-recombinant preparation method of GLP-1 analogue NOVO NORDISK AS 2010-12-08 CN disclosed
US-5854410-A Oligonucleoside cleavage compounds and therapies GENTA INCORPORATED (US) 1998-12-29 US disclosed
EP-0542887-B1 PSORALEN CONJUGATED METHYLPHOSPHONATE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS FOR CHRONIC MYELOGENOUS LEUKEMIA GENTA INC (US) 1998-12-02 EP disclosed
EP-0542887-A1 PSORALEN CONJUGATED METHYLPHOSPHONATE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS FOR CHRONIC MYELOGENOUS LEUKEMIA GENTA INCORPORATED (US) 1993-05-26 EP disclosed
WO-1992002641-A1 PSORALEN CONJUGATED METHYLPHOSPHONATE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS FOR CHRONIC MYELOGENOUS LEUKEMIA GENTA INCORPORATED (US) 1992-02-20 WO disclosed
WO-1992002532-A1 IMPROVED NON-NUCLEOTIDE-BASED LINKER REAGENTS FOR OLIGOMERS GENTA INCORPORATED (US) 1992-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 KMT2A 1391/4885FABP5 1942/4885FABP7 2594/4885
US-20250075259-A1 SELECTIVELY CONTROLLABLE CLEAVABLE LINKERS DNPEP, ADAM8, ADAM10 KMT2A 1657/4885FABP5 4474/4885FABP7 3302/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 KMT2A 4279/4885FABP5 1780/4885FABP7 920/4885
US-20180312500-A9 ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS ITGB1, ITGAV, ITGA1 KMT2A 3854/4885FABP5 2562/4885FABP7 4048/4885
US-12252739-B2 Selectively controllable cleavable linkers DNPEP, ADAM8, ADAM10 KMT2A 1657/4885FABP5 4474/4885FABP7 3302/4885
US-10131658-B2 Anti-alphavbeta1 integrin compounds and methods ITGB1, ITGAV, ITGA1 KMT2A 3854/4885FABP5 2562/4885FABP7 4048/4885
US-20160376266-A1 ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS ITGB1, ITGAV, ITGA1 KMT2A 3854/4885FABP5 2562/4885FABP7 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.