Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504374 | 1.00 | TAAR1 (0.33) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL6650896 | 1.00 | TAAR1 (0.33) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL4504372 | 1.00 | TAAR1 (0.33) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL4494121 | 0.86 | PRSS1 (0.34) | ALDH1A1CYP1A2MEN1KMT2AACE | |
| SCHEMBL7552716 | 0.86 | PRSS1 (0.34) | ALDH1A1CYP1A2MEN1KMT2AACE | |
| SCHEMBL7552725 | 0.86 | PRSS1 (0.34) | ALDH1A1CYP1A2MEN1KMT2AACE | |
| SCHEMBL4494128 | 0.86 | PRSS1 (0.34) | ALDH1A1CYP1A2MEN1KMT2AACE | |
| SCHEMBL10897006 | 0.85 | LDHA (0.41) | SLC6A4ALDH1A1CYP1A2 | |
| SCHEMBL970714 | 0.84 | HTR2A (0.41) | SIGMAR1CYP2A6CYP1A2ACE | |
| SCHEMBL6375850 | 0.83 | PTGER4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695741-B1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0778269-B1 | PROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 2000-09-27 | — | — | EP | disclosed |
| US-5990346-A | AN INHIBITORS OF CELL MIGRATION CAUSED BY CHEMOKINES | TEIJIN LIMITED (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5731452-A | 7-thiaprostaglandins and method of production thereof | TEIJIN LIMITED (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0778269-A1 | PROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0695741-A1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-02-07 | — | — | EP | disclosed |