Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214494 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL6626014 | 0.72 | KDM4E (0.38) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10433439 | 0.69 | GAA (0.47) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10698893 | 0.67 | KDM4E (0.47) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10764117 | 0.67 | KDM4E (0.47) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10515890 | 0.67 | HTR2A (0.51) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10583991 | 0.67 | KDM4E (0.49) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL6831687 | 0.67 | HRH4 (0.41) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10765883 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10515191 | 0.66 | KDM4E (0.47) | ALDH1A1KDM4ETSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392677-A2 | CHIRAL BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | Wockhardt Limited (IN) | 2004-03-03 | — | — | EP | claimed |
| WO-2002085886-A2 | CHIRAL, BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | WOCKHARDT LIMITED (IN) | 2002-10-31 | — | — | WO | claimed |