Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107336 | 0.85 | LMNA (0.42) | TSHRTRPV1TRPA1SPHK1CYP2D6 | |
| SCHEMBL30987409 | 0.84 | TRPV1 (0.52) | TSHRTRPV1TRPA1SPHK1CYP2D6 | |
| SCHEMBL29222445 | 0.84 | TRPV1 (0.43) | TSHRTRPV1TRPA1SPHK1CYP2D6 | |
| SCHEMBL7753996 | 0.83 | TRPV1 (0.36) | TSHRTRPV1TRPA1SPHK1 | |
| SCHEMBL1657239 | 0.82 | TSHR (0.45) | TSHRTDP1 | |
| SCHEMBL31509014 | 0.82 | SPHK1 (0.48) | TSHRTRPV1TRPA1SPHK1TDP1 | |
| SCHEMBL107677 | 0.82 | SPHK1 (0.48) | TSHRTRPV1TRPA1SPHK1TDP1 | |
| SCHEMBL31509114 | 0.82 | SPHK1 (0.48) | TSHRTRPV1TRPA1SPHK1TDP1 | |
| SCHEMBL4883986 | 0.81 | TSHR (0.47) | TSHRTRPV1TRPA1SPHK1TDP1 | |
| SCHEMBL5907121 | 0.80 | PTPN1 (0.41) | TSHRTRPV1TRPA1SPHK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082084-B1 | ANHYDROUS AEROSOL HAIRSPRAY COMPOSITIONS CONTAINING SILICONE GRAFTED COPOLYMERS | PROCTER & GAMBLE (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-1999018929-A1 | PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0611298-A1 | MULTICYCLE REFASTENABLE TAPE CLOSURE SYSTEMS. | MINNESOTA MINING & MFG (US) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993008781-A1 | MULTICYCLE REFASTENABLE TAPE CLOSURE SYSTEMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |