Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319555 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL17255025 | 0.80 | PDE10A (0.43) | CHRM1HRH1KCNH2ALDH1A1CHEK2 | |
| SCHEMBL6312089 | 0.80 | KDM4E (0.46) | CHRM1HRH1KCNH2ALDH1A1CHEK2 | |
| SCHEMBL6313030 | 0.79 | ALDH1A1 (0.44) | CHRM1HRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL17255021 | 0.79 | DYRK1A (0.42) | CHRM1HRH1KCNH2ALDH1A1CHEK2 | |
| SCHEMBL17255049 | 0.79 | HRH1 (0.42) | CHRM1HRH1KCNH2ALDH1A1KDM4E | |
| SCHEMBL14728639 | 0.78 | MAPK1 (0.61) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL23161470 | 0.78 | HRH1 (0.40) | CHRM1HRH1KCNH2ALDH1A1CHEK2 | |
| SCHEMBL18057438 | 0.78 | HRH1 (0.40) | CHRM1HRH1KCNH2ALDH1A1CHEK2 | |
| SCHEMBL5452911 | 0.78 | MAPK8 (0.42) | CHEK2HTR1DHTR3AHTR6TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |