SCHEMBL6651767

SCHEMBL6651767

O=C1CC(C2CO2)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.43
CRBN Q96SW2 1/20 0.36
PTPN1 P18031 2/20 0.34
PRKCG P05129 1/20 0.34
CYP19A1 P11511 1/20 0.33
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5909391 0.80 MAP3K14 (0.55) MAP3K14CRBNCYP19A1IDO1
SCHEMBL11103792 0.74 CA1 (0.36) MAP3K14CRBNPTPN1PRKCG
SCHEMBL24490044 0.70 MAP3K14 (0.44) MAP3K14CRBNCYP19A1IDO1
SCHEMBL18643159 0.68 MAP3K14 (0.48) MAP3K14CRBNCYP19A1IDO1
SCHEMBL6897659 0.67
SCHEMBL8499277 0.67
SCHEMBL11719476 0.67 MAP3K14 (0.46) MAP3K14CRBNCYP19A1
SCHEMBL27815633 0.65 GLA (0.41) MAP3K14CRBNCYP19A1
SCHEMBL31536451 0.63 MAP3K14 (0.31) MAP3K14
SCHEMBL2958336 0.63 MAP3K14 (0.42) MAP3K14CRBNCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425443-A1 BRANCHED POLY(ETHYLENE TEREPHTHALATE) MONOFILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-06-09 EP disclosed
WO-2003014439-A1 BRANCHED POLY(ETHYLENE TEREPHTHALATE) MONOFILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-20 WO disclosed