Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 1.00 |
| ▸ | FFAR1 | O14842 | 2/20 | 1.00 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 1.00 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | PPARD | Q03181 | 6/20 | 0.57 |
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984387 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984655 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Sebacic Acid SCHEMBL11410575 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984473 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984619 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| 1,6-Hexanediol SCHEMBL8737411 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL16113 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| 1,5-Pentanediol SCHEMBL20696141 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL21114450 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984680 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807135-A4 | IMPACT RESISTANT POLYURETHANE AND METHOD OF MANUFACTURE THEREOF | SIMULA INC (US) | 1998-03-18 | — | — | EP | claimed |
| EP-0807135-A1 | IMPACT RESISTANT POLYURETHANE AND METHOD OF MANUFACTURE THEREOF | SIMULA INC. (US) | 1997-11-19 | — | — | EP | claimed |
| WO-1996023827-A1 | IMPACT RESISTANT POLYURETHANE AND METHOD OF MANUFACTURE THEREOF | SIMULA INC. (US) | 1996-08-08 | — | — | WO | claimed |
| US-12377688-B2 | Tyre for vehicle wheels | PIRELLI TYRE S.P.A. (IT) | 2025-08-05 | — | — | US | disclosed |
| EP-3802113-B1 | TYRE FOR VEHICLE WHEELS | PIRELLI (IT) | 2024-02-07 | — | — | EP | disclosed |
| CN-112351880-B | Tyre for vehicle wheels | 倍耐力轮胎股份公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-112262048-B | Tyre for vehicle wheels | 倍耐力轮胎股份公司 | 2022-11-15 | — | — | CN | disclosed |
| EP-3807106-B1 | TYRE FOR VEHICLE WHEELS | PIRELLI (IT) | 2022-08-03 | — | — | EP | disclosed |
| US-20210229505-A1 | TYRE FOR VEHICLE WHEELS | PIRELLI TYRE S.P.A. (IT) | 2021-07-29 | — | — | US | disclosed |
| CN-112351880-A | Tyre for vehicle wheels | 倍耐力轮胎股份公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112262048-A | Tyre for vehicle wheels | 倍耐力轮胎股份公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-105899563-B | Composition and optical article containing polyurethaneurea and method of making the same | PPG工业俄亥俄公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-108690180-A | Composition and optical goods containing polyurethane-urea and preparation method thereof | PPG工业俄亥俄公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107922578-A | It is used to prepare the composition of molded polymer article | PPG工业俄亥俄公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105899563-A | Composition and optical article containing polyurethaneurea and method of making the same | PPG工业俄亥俄公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-0807135-B1 | IMPACT RESISTANT POLYURETHANE AND METHOD OF MANUFACTURE THEREOF | SIMULA INC (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-1996023827-A1 | IMPACT RESISTANT POLYURETHANE AND METHOD OF MANUFACTURE THEREOF | SIMULA INC. (US) | 1996-08-08 | — | — | WO | disclosed |