Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068829 | 0.95 | CA12 (0.41) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4950570 | 0.91 | CA12 (0.41) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL6068947 | 0.91 | GAA (0.45) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL28268790 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1MEN1KMT2AKDM6B | |
| SCHEMBL24834901 | 0.81 | GRM2 (0.41) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3904050 | 0.80 | NOTUM (0.49) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2501250 | 0.78 | CA12 (0.50) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6632862 | 0.77 | SMN1; SMN2 (0.38) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL22077172 | 0.76 | NOTUM (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27902795 | 0.76 | ACMSD (0.52) | KDM4EALDH1A1GAAACMSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377584-A1 | NOVEL CYCLOHEXENYL PHENYL DIAZEPINES AS VASOPRESSIN AND OXYTOCIN RECEPTOR MODULATORS | Wyeth (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083681-A1 | NOVEL CYCLOHEXENYL PHENYL DIAZEPINES VASOPRESSIN AND OXYTOCIN RECEPTOR MODULATORS | WYETH (US) | 2002-10-24 | — | — | WO | disclosed |