Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787563 | 1.00 | TSHR (0.59) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL163992 | 0.94 | TSHR (0.58) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL1405467 | 0.82 | ALDH1A1 (0.81) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL3217829 | 0.82 | ALDH1A1 (0.81) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL333218 | 0.82 | CYP3A4 (0.61) | TSHRALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL333217 | 0.82 | CYP3A4 (0.61) | TSHRALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL3217840 | 0.82 | ALDH1A1 (0.81) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL1405466 | 0.82 | ALDH1A1 (0.81) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL3217836 | 0.82 | ALDH1A1 (0.81) | TSHRALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL9185385 | 0.81 | TSHR (0.50) | TSHRALDH1A1MAPK1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787330-B1 | USING POLYACRYLAMIDE GEL ELECTROPHORESIS (PAGE); PROTEOMICS; BLOT ANALYSIS | UNIVERSITY OF GENEVA (CH) | 2004-09-07 | — | — | US | disclosed |
| EP-1147414-B1 | METHOD AND KIT FOR IDENTIFYING OR CHARACTERISING POLYPEPTIDES | UNIV GENEVE (CH) | 2004-06-09 | — | — | EP | disclosed |