Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | LITAF | Q99732 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643132 | 0.88 | TLR8 (0.55) | TLR8PKMMEN1KMT2ACASR | |
| SCHEMBL6954581 | 0.80 | TLR8 (0.54) | TLR8PKMMEN1KMT2ACASR | |
| SCHEMBL6652836 | 0.79 | NQO2 (0.49) | TLR8PKMMEN1KMT2ACASR | |
| SCHEMBL16512961 | 0.74 | TLR8 (1.00) | TLR8CASRMAPTPOLBTP53 | |
| SCHEMBL14685298 | 0.73 | PDE10A (0.53) | TLR8PKMMEN1KMT2ACASR | |
| SCHEMBL30524217 | 0.70 | GRM2 (0.49) | TLR8MEN1KMT2ACASRALDH1A1 | |
| SCHEMBL194252 | 0.69 | TLR8 (0.48) | TLR8PKMCASRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7707554 | 0.69 | TLR8 (0.48) | TLR8PKMCASRSMN1; SMN2NQO2 | |
| SCHEMBL29795694 | 0.69 | ASAH1 (0.54) | TLR8CASRTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28945638 | 0.69 | ASAH1 (0.54) | TLR8CASRTSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |