SCHEMBL6652196

SCHEMBL6652196

COc1ccccc1Nc1c(F)c2c(c(F)c1Nc1ccccc1OC)C(=O)c1ccccc1C2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
MAPK1 P28482 7/20 0.58
POLB P06746 4/20 0.58
KDM4E B2RXH2 3/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
ALDH1A1 P00352 7/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MCL1 Q07820 1/20 0.52
ATM Q13315 1/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
USP2 O75604 1/20 0.51
DUSP3 P51452 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
P2RY2 P41231 2/20 0.51
P2RY4 P51582 2/20 0.51
STK10 O94804 1/20 0.50
SLK Q9H2G2 1/20 0.50
RAB9A P51151 5/20 0.48
NPC1 O15118 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502805 0.94 MAPT (0.56) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL6651233 0.94 MAPT (0.56) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL29460865 0.87 MAPT (0.53) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL7933112 0.86 EGFR (0.51) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL6651932 0.82 MAPT (0.47) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL29502784 0.82 MAPT (0.47) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL8618796 0.81 MAPT (0.65) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL7921212 0.81 EGFR (0.49) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL27375318 0.79 MAPT (0.61) MAPTMAPK1POLBKDM4EL3MBTL1
SCHEMBL7924525 0.78 MAPT (0.60) MAPTMAPK1POLBKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833203-B1 Anthraquinone compounds NIPPON CATALYTIC CHEM IND (JP) 2004-06-16 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed