Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.62 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | STK10 | O94804 | 1/20 | 0.55 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037866 | 0.91 | MAPT (0.64) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL27375318 | 0.90 | MAPT (0.61) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL7924525 | 0.90 | MAPT (0.60) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL8771240 | 0.83 | EGFR (0.55) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL11795532 | 0.82 | EGFR (0.51) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL6652196 | 0.81 | MAPT (0.58) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL6055437 | 0.81 | P2RY4 (0.69) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL3191755 | 0.80 | MAPT (0.69) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL6651233 | 0.79 | MAPT (0.56) | MAPTMAPK1KDM4EL3MBTL1POLB | |
| SCHEMBL29502805 | 0.79 | MAPT (0.56) | MAPTMAPK1KDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716666-B1 | TONERS FOR POLYESTERS | EASTMAN CHEM CO (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0716666-A1 | TONERS FOR POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995006677-A1 | TONERS FOR POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1995-03-09 | — | — | WO | disclosed |
| US-5384377-A | Anthraquinone and anthrapyridone compounds provide neutral to blue hue to yellow-appearing polyesters | EASTMAN CHEMICAL COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5372864-A | Whiteners | EASTMAN CHEMICAL COMPANY (US) | 1994-12-13 | — | — | US | disclosed |