SCHEMBL6652291

SCHEMBL6652291

CCC(C)(C)c1ccc(OCCCC[C]=O)c(C(C)(C)CC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.59
NPSR1 Q6W5P4 5/20 0.59
SMN1; SMN2 Q16637 5/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
MAPT P10636 4/20 0.59
HTT P42858 3/20 0.59
UBE2N P61088 2/20 0.59
GLA P06280 1/20 0.59
MITF O75030 1/20 0.59
ALDH1A1 P00352 1/20 0.54
RAD52 P43351 2/20 0.54
RAB9A P51151 2/20 0.54
STAT3 P40763 1/20 0.54
RCE1 Q9Y256 1/20 0.54
APAF1 O14727 1/20 0.54
HSP90AA1 P07900 1/20 0.54
NOD2 Q9HC29 1/20 0.54
RRM1 P23921 1/20 0.41
SIRT2 Q8IXJ6 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121430 0.96 MAPK1 (0.57) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11776594 0.86 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6536664 0.85 MAPK1 (0.63) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8593377 0.84 MAPK1 (0.66) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7208730 0.84 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL77092 0.83 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8595365 0.83 MAPK1 (0.64) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11272885 0.83 MAPK1 (0.64) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7767137 0.83 MAPK1 (0.61) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9769466 0.83 MAPK1 (0.64) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109061-B1 Silver halide color photographic light sensitive material KONISHIROKU PHOTO IND (JP) 2004-06-09 EP disclosed
US-6403293-B2 3-ANILINO-5-PYRAZOLONE COUPLER; STORAGE STABILITY KONICA CORPORATION (JP) 2002-06-11 US disclosed
US-20010008749-A1 Silver halide color photographic light sensitive material KONICA CORPORATION (JP) 2001-07-19 US disclosed
EP-1109061-A1 Silver halide color photographic light sensitive material KONICA CORPORATION (JP) 2001-06-20 EP disclosed