SCHEMBL7208730

SCHEMBL7208730

CCC(C)(C)c1ccc(OCCCO[C]=O)c(C(C)(C)CC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 7/20 0.56
NPSR1 Q6W5P4 6/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
MAPT P10636 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
HTT P42858 3/20 0.56
UBE2N P61088 2/20 0.56
GLA P06280 1/20 0.56
MITF O75030 1/20 0.56
ALDH1A1 P00352 1/20 0.54
RAD52 P43351 2/20 0.51
RAB9A P51151 2/20 0.51
STAT3 P40763 1/20 0.51
RCE1 Q9Y256 1/20 0.51
APAF1 O14727 1/20 0.51
HSP90AA1 P07900 1/20 0.51
NOD2 Q9HC29 1/20 0.51
RRM1 P23921 1/20 0.39
SIRT2 Q8IXJ6 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776594 0.97 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL11775931 0.93 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL2121430 0.85 MAPK1 (0.57) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL6652291 0.84 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL7767137 0.83 MAPK1 (0.61) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL9083094 0.83 MAPK1 (0.64) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL5147880 0.82 MAPK1 (0.43) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL6536664 0.82 MAPK1 (0.63) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL1081181 0.82 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MAPTMEN1
SCHEMBL8593377 0.81 MAPK1 (0.66) MAPK1NPSR1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903350-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 2003-03-12 EP disclosed
EP-0518238-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 1999-04-07 EP disclosed
EP-0903350-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
US-5508421-A Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1996-04-16 US disclosed
US-5362882-A Intermediates for dyes for polyesters, images for heat sensitive elements and electrography FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0285176-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-08 EP disclosed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP disclosed
US-5118597-A Sharpness, grainness, color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1992-06-02 US disclosed
US-4985336-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-15 US disclosed
US-4933989-A Excellent color reproduction; sharpness FUJI PHOTO FILM CO. 1990-06-12 US disclosed
US-4873179-A MOLD RESISTANCE; ANTISOILANTS; COLORFASTNESS; RELEASE OF DEVELOPMENT INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1989-10-10 US disclosed
US-4824772-A COLOR PHOTOGRAPHY; SHARP IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed
US-4818664-A AFTER DEVELOPMENT USING A BLEACHING SOLUTION CONTAINING AN AMINOPOLYCARBOXYLIC ACID FERRIC COMPLEX SALT OXIDIZER FOR DEMETALLIZATION FUJI PHOTO FILM CO., LTD. (JP) 1989-04-04 US disclosed
EP-0285176-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP disclosed
US-4770982-A Silver halide photographic materials containing a compound which releases a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed