Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL665233

N.NC(=O)CCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.54
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
HDAC6 Q9UBN7 1/20 0.48
MEN1 O00255 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
KMT2A Q03164 2/20 0.40
FAAH O00519 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
SOAT1 P35610 1/20 0.40
PRMT1 Q99873 1/20 0.39
CA12 O43570 1/20 0.39
F13A1 P00488 1/20 0.39
CA2 P00918 1/20 0.39
ALOX15 P16050 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30777862 0.95 PAOX (0.54) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL30124191 0.95 PAOX (0.54) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL10424784 0.95 PAOX (0.54) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL31271806 0.92 MAOA (0.54) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL6886496 0.90 PAOX (0.61) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL6888821 0.90 PAOX (0.61) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL2311032 0.90 PAOX (0.61) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL11310703 0.90 PAOX (0.61) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL6536854 0.88 MAOA (0.69) PAOXMAOAMAOBHDAC6MEN1
SCHEMBL18342530 0.88 MAOA (0.69) PAOXMAOAMAOBHDAC6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1322705-B1 THERMOPLASTIC MOULDING MATERIALS WITH SPECIAL ADDITIVE MIXTURES INEOS ABS JERSEY LTD (GB) 2009-05-06 EP claimed
US-20120046401-A1 METHOD FOR THE REDUCTION OF POLAR ADDITIVES REQUIRED FOR USE IN POLYOLEFINS DOW GLOBAL TECHNOLOGIES INC. (US) 2012-02-23 US disclosed
EP-0984994-A1 ABS MOLDING MATERIALS WITH ENHANCED WORKING PROPERTIES Bayer Aktiengesellschaft (DE) 2000-03-15 EP disclosed
WO-1998054238-A1 ABS MOLDING MATERIALS WITH ENHANCED WORKING PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1998-12-03 WO disclosed
EP-0730614-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYURETHANES BY COMBINED THETHERMOPLASTIC TREATMENT OF A HYDROXYL- AND AN ISOCYANATE POLYURETHANE BAYER AG (DE) 1996-09-11 EP disclosed
WO-1995014723-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYURETHANES BY COMBINED THETHERMOPLASTIC TREATMENT OF A HYDROXYL- AND AN ISOCYANATE POLYURETHANE BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
EP-0412371-A1 ABS mouldings with improved tensile stress BAYER AG (DE) 1991-02-13 EP disclosed