Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12156956 | 0.84 | LMNA (0.61) | LMNACA12CA1CA2CA3 | |
| SCHEMBL1029527 | 0.82 | LMNA (0.47) | LMNACA12CA1CA2CA3 | |
| SCHEMBL275373 | 0.81 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL13259747 | 0.81 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10031602 | 0.81 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4400630 | 0.81 | LMNA (0.58) | LMNACA12CA1CA2CA3 | |
| SCHEMBL23758301 | 0.79 | LMNA (0.56) | LMNACA12CA1CA2CA3 | |
| SCHEMBL1304503 | 0.79 | LMNA (0.61) | LMNACA12CA1CA2CA3 | |
| Methane SCHEMBL29452825 | 0.79 | LMNA (0.56) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2457545 | 0.79 | LMNA (0.61) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432405-A1 | IBUPROFEN SALT EMULSIFIERS AND CREAM FORMULATIONS CONTAINING SAME | MacroChem Corporation (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028702-A1 | IBUPROFEN SALT EMULSIFIERS AND CREAM FORMULATIONS CONTAINING SAME | MACROCHEM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |
| EP-0934080-A2 | 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015291-A1 | 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |