Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651727 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL1609515 | 0.97 | LPAR3 (0.38) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL23493367 | 0.92 | LPAR3 (0.43) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL27678082 | 0.91 | LPAR3 (0.34) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL7012322 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL28367822 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL9009725 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL4810661 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL10390610 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 | |
| SCHEMBL9009701 | 0.90 | LPAR3 (0.41) | LPAR3LPAR2THRBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | claimed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | claimed |
| EP-1178077-B1 | The preparation of surface modified silica | GOODYEAR TIRE & RUBBER (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5916973-A | Na, K and Li salts of siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0794188-A1 | Na, k and Li salts of siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0646672-B1 | Coated fabrics for air bags | WACKER CHEMIE GMBH (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0582972-B1 | Detergent resistant compositions | WACKER CHEMIE GMBH (DE) | 1995-10-25 | — | — | EP | disclosed |
| EP-0646672-A1 | Coated fabrics for air bags | Wacker-Chemie GmbH (DE) | 1995-04-05 | — | — | EP | disclosed |
| US-5401566-A | Polysiloxane coating | WACKER SILICONES CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0582972-A2 | Detergent resistant compositions | Wacker-Chemie GmbH (DE) | 1994-02-16 | — | — | EP | disclosed |
| US-5264027-A | Polysiloxanes | WACKER SILICONES CORPORATION (US) | 1993-11-23 | — | — | US | disclosed |
| US-4218354-A | HYDROLYZED ORGANOTRIALKOXYSILANE | STAUFFER CHEMICAL COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | LPAR3 3044/4885LPAR2 1567/4885THRB 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.