Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17296975 | 0.91 | ALDH1A1 (0.61) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL822041 | 0.90 | PARP1 (0.63) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL12792079 | 0.89 | CNR2 (0.57) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL9973084 | 0.87 | PBRM1 (0.69) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL822045 | 0.86 | ALDH1A1 (0.67) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL822173 | 0.86 | ALDH1A1 (0.67) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL30195107 | 0.86 | ALDH1A1 (0.67) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL203108 | 0.86 | PBRM1 (0.67) | POLBLMNANPC1MITFPBRM1 | |
| SCHEMBL186545 | 0.86 | PARP1 (0.68) | MAPK13MAPK12MAPK11MAPK14PARP1 | |
| SCHEMBL29503529 | 0.86 | PARP1 (0.68) | MAPK13MAPK12MAPK11MAPK14PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040793-A1 | ANTI-INFLAMMATORY COMPOUND AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2023-03-23 | — | — | WO | disclosed |
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |
| EP-0966424-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998032730-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-07-30 | — | — | WO | disclosed |
| US-4346046-A | FROM AMINOARYL-B-HYDROXYETHYLSULFONE AND SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-24 | — | — | US | disclosed |