Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.36 |
| ▸ | MAP3K4 | Q9Y6R4 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652093 | 0.89 | CXCR4 (0.54) | CXCR4MAPK14DDR1DDR2GPR88 | |
| SCHEMBL6653505 | 0.88 | CXCR4 (0.54) | CXCR4MAPK14DDR1DDR2GPR88 | |
| SCHEMBL6018195 | 0.86 | CXCR4 (0.46) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL6652160 | 0.85 | CXCR4 (0.45) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL6657781 | 0.84 | CXCR4 (0.43) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL7023773 | 0.81 | CXCR4 (0.46) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL6652655 | 0.80 | CXCR4 (0.43) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL6019474 | 0.80 | HDAC1 (0.45) | CXCR4HDAC3HDAC1HDAC2MAPK14 | |
| SCHEMBL6018294 | 0.80 | CXCR4 (0.41) | CXCR4HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL6018022 | 0.80 | CXCR4 (0.41) | CXCR4HDAC3HDAC1HDAC2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254221-A1 | Novel Nitrogenous Compound and use thereof | KUREHA CORPORATION (JP) | 2004-12-16 | — | — | US | claimed |
| EP-1431290-A1 | NOVEL NITROGENOUS COMPOUND AND USE THEREOF | Kureha Chemical Industry Co., Ltd. (JP) | 2004-06-23 | — | — | EP | claimed |
| US-20040254221-A1 | Novel Nitrogenous Compound and use thereof | KUREHA CORPORATION (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1431290-A1 | NOVEL NITROGENOUS COMPOUND AND USE THEREOF | Kureha Chemical Industry Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254221-A1 | Novel Nitrogenous Compound and use thereof | NGLY1, NOD1, CCR1 | CXCR4 88/4885HDAC3 1711/4885HDAC1 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.