Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652981 | 1.00 | CYP4F2 (0.40) | CYP4F2CYP4A11NPSR1GLO1FAAH | |
| SCHEMBL16001855 | 0.89 | NPSR1 (0.39) | CYP4F2CYP4A11NPSR1GLO1FAAH | |
| SCHEMBL14721786 | 0.84 | FAAH (0.54) | NPSR1FAAHCYP1A2MEN1MAPT | |
| SCHEMBL31190390 | 0.84 | FAAH (0.54) | NPSR1FAAHCYP1A2MEN1MAPT | |
| SCHEMBL14721787 | 0.84 | FAAH (0.54) | NPSR1FAAHCYP1A2MEN1MAPT | |
| SCHEMBL14616333 | 0.82 | NPSR1 (0.41) | NPSR1GLO1FAAHCYP1A2ALDH1A1 | |
| SCHEMBL13429276 | 0.82 | NPSR1 (0.41) | NPSR1GLO1FAAHCYP1A2ALDH1A1 | |
| SCHEMBL31547163 | 0.81 | FAAH (0.44) | NPSR1FAAHCYP1A2ALDH1A1MAPT | |
| SCHEMBL9322499 | 0.81 | FAAH (0.59) | NPSR1FAAHCYP1A2MEN1MAPT | |
| SCHEMBL13772346 | 0.81 | CYP1A2 (0.42) | NPSR1GLO1FAAHCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110943-B1 | 6-FLUOROBICYCLO 3. 1.0]HEXANE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6333428-B1 | TREATMENT OR PREVENTION OF PSYCHIATRIC DISORDERS OR NEUROLOGICAL DISEASES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1110943-A1 | 6-FLUOROBICYCLO 3. 1.0]HEXANE DERIVATIVES | Taisho Pharmaceutical Co. Ltd. (JP) | 2001-06-27 | — | — | EP | disclosed |