Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651019 | 0.99 | MEN1 (0.41) | MEN1KMT2APANK3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6653311 | 0.98 | MEN1 (0.41) | MEN1KMT2APANK3ALDH1A1LMNA | |
| Hypochlorous Acid SCHEMBL6652392 | 0.89 | HCRTR1 (0.44) | MEN1KMT2AALDH1A1LMNAHRH2 | |
| SCHEMBL6652566 | 0.88 | HCRTR1 (0.45) | MEN1KMT2AALDH1A1LMNAHRH2 | |
| Hypochlorous Acid SCHEMBL6657831 | 0.87 | HRH2 (0.43) | MEN1KMT2APANK3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6652387 | 0.87 | HCRTR1 (0.44) | MEN1KMT2AALDH1A1LMNAHRH2 | |
| SCHEMBL6651929 | 0.86 | HRH2 (0.44) | MEN1KMT2APANK3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6657823 | 0.85 | HRH2 (0.43) | MEN1KMT2APANK3ALDH1A1LMNA | |
| Hypochlorous Acid SCHEMBL6650991 | 0.78 | HCRTR1 (0.48) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| Hypochlorous Acid SCHEMBL6658317 | 0.78 | L3MBTL1 (0.60) | MEN1KMT2AALDH1A1SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |