SCHEMBL6653369

SCHEMBL6653369

CCCCCCCCc1ccc(C(=O)O)s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 2/20 0.58
LMNA P02545 1/20 0.58
PRNP P04156 1/20 0.58
RECQL P46063 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
HPGD P15428 1/20 0.50
PTGER2 P43116 6/20 0.48
PTGER3 P43115 4/20 0.48
PTGDR Q13258 3/20 0.48
PTGER1 P34995 1/20 0.48
GPR35 Q9HC97 2/20 0.48
PTGER4 P35408 2/20 0.46
RARB P10826 4/20 0.45
MEN1 O00255 1/20 0.45
RARA P10276 1/20 0.45
MAPT P10636 1/20 0.45
MTOR P42345 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971941 1.00 POLB (0.59) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL8971725 1.00 POLB (0.59) POLBTDP1ALDH1A1LMNAPRNP
Hydrochloric Acid SCHEMBL8998499 0.98 POLB (0.57) POLBTDP1ALDH1A1LMNAPRNP
Hydrochloric Acid SCHEMBL8998584 0.98 POLB (0.57) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL846642 0.98 POLB (0.56) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL261238 0.93 POLB (0.54) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL21199842 0.89 POLB (0.49) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL21199691 0.87 HPGD (0.48) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL20852636 0.87 POLB (0.47) POLBTDP1ALDH1A1LMNAPRNP
SCHEMBL3176363 0.86 LMNA (0.71) POLBTDP1ALDH1A1LMNAPRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1147162-B1 FERROELECTRIC ACTIVE MATRIX DISPLAYS WITH WIDE OPERATING TEMPERATURE RANGE CLARIANT GMBH (DE) 2004-06-09 EP disclosed
US-6746731-B1 ACHIEVES VERY HIGH MAXIMUM TRANSMISSION AND VERY HIGH CONTRAST AND CONSTANT THRESHOLD VOLTAGE OVER BROAD TEMPERATURE RANGE CLARIANT GMBH (DE) 2004-06-08 US disclosed
EP-1147162-A1 FERROELECTRIC ACTIVE MATRIX DISPLAYS WITH WIDE OPERATING TEMPERATURE RANGE Clariant GmbH (DE) 2001-10-24 EP disclosed
WO-2000036054-A1 FERROELECTRIC ACTIVE MATRIX DISPLAYS WITH WIDE OPERATING TEMPERATURE RANGE CLARIANT GMBH (DE) 2000-06-22 WO disclosed
EP-0476567-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-06-12 EP disclosed
US-5217645-A Low temperature, high speed response CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
EP-0476567-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-03-25 EP disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 US disclosed