Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653398 | 1.00 | MAPT (0.51) | MAPTLMNAGSK3BHIF1AALDH1A1 | |
| SCHEMBL6653611 | 0.85 | NPC1 (0.52) | MAPTLMNAALDH1A1NPC1TP53 | |
| SCHEMBL6653609 | 0.85 | NPC1 (0.52) | MAPTLMNAALDH1A1NPC1TP53 | |
| SCHEMBL308686 | 0.83 | HIF1A (0.55) | MAPTLMNAGSK3BHIF1AALDH1A1 | |
| SCHEMBL1239191 | 0.80 | HIF1A (0.58) | MAPTLMNAGSK3BHIF1AALDH1A1 | |
| SCHEMBL307839 | 0.79 | GSK3B (0.54) | MAPTLMNAGSK3BHIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6653664 | 0.79 | RAB9A (0.61) | MAPTLMNAALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6653662 | 0.79 | RAB9A (0.61) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL6689013 | 0.78 | MAPT (0.53) | MAPTLMNAGSK3BHIF1AALDH1A1 | |
| SCHEMBL6689008 | 0.78 | MAPT (0.53) | MAPTLMNAGSK3BHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061134-A9 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2004-04-22 | — | — | WO | disclosed |
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |