Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | GAA | P10253 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | APAF1 | O14727 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | GLA | P06280 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651847 | 0.93 | KDM4E (0.66) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6311488 | 0.80 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6652182 | 0.80 | KDM4E (0.72) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6311878 | 0.76 | KDM4E (0.91) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6318629 | 0.73 | HPGD (0.64) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6652217 | 0.72 | KDM4E (0.81) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6649341 | 0.72 | KDM4E (0.75) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6313764 | 0.72 | KDM4E (0.72) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6312322 | 0.71 | RAB9A (0.64) | KDM4EGAAALDH1A1HPGDHTT | |
| SCHEMBL6311835 | 0.69 | KDM4E (0.80) | KDM4EGAAALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |