Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | THRA | P10827 | 9/20 | 0.57 |
| ▸ | THRB | P10828 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086601 | 0.98 | THRA (0.59) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL11202747 | 0.98 | THRA (0.59) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL10580743 | 0.95 | RARB (0.57) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL617127 | 0.91 | RARB (0.68) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL16536411 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL7652503 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL15453509 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL7649277 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL2970920 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A | |
| SCHEMBL28963426 | 0.89 | THRA (0.69) | RARBTHRATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |
| EP-0966424-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998032730-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-07-30 | — | — | WO | disclosed |
| EP-0302401-A1 | Pyridone dyes, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |